![MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition | IMB Inflammasome Lab MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition | IMB Inflammasome Lab](https://inflammasomelab.com/sites/inflammasomelab.com/files/graphical%20abstract_KS2-01.jpg)
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition | IMB Inflammasome Lab
![Genes | Free Full-Text | A Novel Function for the Conserved Glutamate Residue in the Walker B Motif of Replication Factor C Genes | Free Full-Text | A Novel Function for the Conserved Glutamate Residue in the Walker B Motif of Replication Factor C](https://pub.mdpi-res.com/genes/genes-04-00134/article_deploy/html/images/genes-04-00134-g002.png?1571993655)
Genes | Free Full-Text | A Novel Function for the Conserved Glutamate Residue in the Walker B Motif of Replication Factor C
![A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0022283620304812-ga1.jpg)
A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect
![Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function | BMC Microbiology | Full Text Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function | BMC Microbiology | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12866-016-0629-3/MediaObjects/12866_2016_629_Fig1_HTML.gif)
Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function | BMC Microbiology | Full Text
![A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0022283620304812-gr1.jpg)
A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect
![A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0022283620304812-gr6.jpg)
A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases - ScienceDirect
The ATPase site and mutations affecting SecA function. (a) The Walker A... | Download Scientific Diagram
![Figure 1 from Role of highly central residues of P-loop and it's flanking region in preserving the archetypal conformation of Walker A motif of diverse P-loop NTPases | Semantic Scholar Figure 1 from Role of highly central residues of P-loop and it's flanking region in preserving the archetypal conformation of Walker A motif of diverse P-loop NTPases | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/c66c4c33a46b5b18220c562e1a90a98622e15c06/2-Figure1-1.png)
Figure 1 from Role of highly central residues of P-loop and it's flanking region in preserving the archetypal conformation of Walker A motif of diverse P-loop NTPases | Semantic Scholar
![Visualization of NBD motifs: The NBD-NBD interface of a single NBD is shown in cartoon representation. Visualization of NBD motifs: The NBD-NBD interface of a single NBD is shown in cartoon representation.](https://s3-eu-west-1.amazonaws.com/ppreviews-plos-725668748/25002971/preview.jpg)
Visualization of NBD motifs: The NBD-NBD interface of a single NBD is shown in cartoon representation.
![ATP-dependent conformational change in ABC-ATPase RecF serves as a switch in DNA repair | Scientific Reports ATP-dependent conformational change in ABC-ATPase RecF serves as a switch in DNA repair | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-018-20557-0/MediaObjects/41598_2018_20557_Fig1_HTML.jpg)
ATP-dependent conformational change in ABC-ATPase RecF serves as a switch in DNA repair | Scientific Reports
![Model of the NOD2 nucleotide-binding site with an ADP molecule and conserved sequence motifs Walker A, Walker B, Sensor 1, GxP, and WH-His shown in sticks. Model of the NOD2 nucleotide-binding site with an ADP molecule and conserved sequence motifs Walker A, Walker B, Sensor 1, GxP, and WH-His shown in sticks.](https://s3-eu-west-1.amazonaws.com/ppreviews-plos-725668748/933173/preview.jpg)
Model of the NOD2 nucleotide-binding site with an ADP molecule and conserved sequence motifs Walker A, Walker B, Sensor 1, GxP, and WH-His shown in sticks.
![PDF] The Walker B motif of the second nucleotide-binding domain (NBD2) of CFTR plays a key role in ATPase activity by the NBD1-NBD2 heterodimer. | Semantic Scholar PDF] The Walker B motif of the second nucleotide-binding domain (NBD2) of CFTR plays a key role in ATPase activity by the NBD1-NBD2 heterodimer. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/fb03c57d46cf8f1d0e5151dfa451ac68d4a2966f/3-Figure1-1.png)
PDF] The Walker B motif of the second nucleotide-binding domain (NBD2) of CFTR plays a key role in ATPase activity by the NBD1-NBD2 heterodimer. | Semantic Scholar
![Toward wide-spectrum antivirals against coronaviruses: Molecular characterization of SARS-CoV-2 NSP13 helicase inhibitors | Science Advances Toward wide-spectrum antivirals against coronaviruses: Molecular characterization of SARS-CoV-2 NSP13 helicase inhibitors | Science Advances](https://www.science.org/cms/10.1126/sciadv.abj4526/asset/1c906d5b-9c93-4a05-a9ba-824802094abc/assets/images/large/sciadv.abj4526-f1.jpg)
Toward wide-spectrum antivirals against coronaviruses: Molecular characterization of SARS-CoV-2 NSP13 helicase inhibitors | Science Advances
![Snapshot of Walker A motif configuration in an NTP hydrolysis cycle.... | Download Scientific Diagram Snapshot of Walker A motif configuration in an NTP hydrolysis cycle.... | Download Scientific Diagram](https://www.researchgate.net/publication/311492087/figure/fig5/AS:625534010662913@1526150338991/Snapshot-of-Walker-A-motif-configuration-in-an-NTP-hydrolysis-cycle-The-actual-structure.png)
Snapshot of Walker A motif configuration in an NTP hydrolysis cycle.... | Download Scientific Diagram
![SOLVED: The Walker A motif is protein structure element frequently observed in nucleotide hydrolases; which are enzymes that couple the energy released by breaking phosphate bonds with other reactions In the CH] SOLVED: The Walker A motif is protein structure element frequently observed in nucleotide hydrolases; which are enzymes that couple the energy released by breaking phosphate bonds with other reactions In the CH]](https://cdn.numerade.com/ask_images/9ecd6341cb4e4ea591d6564f0329d87f.jpg)